Medical Disclaimer

Medical Disclaimer

Polygenic risk scores are not a diagnosis

The scores produced by Genetic Psychiatric Insights summarize the combined statistical effect of many genetic variants on a given trait. They describe propensities, not certainties. A high score does not mean you have or will develop a condition, and a low score does not mean you are free from risk. Many factors beyond genetics — environment, lifestyle, medical history — influence actual outcomes.

Not a substitute for clinical evaluation

Nothing in a Genetic Psychiatric Insights report should be interpreted as medical advice, a clinical recommendation, or a substitute for evaluation by a qualified healthcare professional. Do not start, stop, or change any treatment based on a polygenic risk score without first consulting your clinician.

Not actionable without professional guidance

Polygenic scores are research tools. They are useful for understanding population-level genetic architecture, but they are not validated for individual clinical decision-making. Any action you take based on your report is your own responsibility and should involve professional medical guidance.

Ancestry calibration caveat

The GWAS summary statistics used by Genetic Psychiatric Insights are predominantly derived from cohorts of European ancestry. Polygenic scores calculated from these statistics are most predictive for individuals of similar genetic background. For individuals of non-European or mixed ancestry, the scores may be less accurate, less predictive, or misleading. This is a known limitation of current GWAS research, not a design choice.

Scores are propensities, not certainties

A polygenic risk score captures a fraction of the total genetic contribution to a trait, which is itself only a fraction of the total risk. Two people with the same score can have very different health outcomes. Treat your score as one data point among many, not as a verdict.

Last updated: April 2026